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The Management Of Resistant Depression.

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Guest allanopie

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Guest allanopie

1: Acta Psychiatr Belg. 1986 Mar-Apr;86(2):141-51.

The management of resistant depression.

Levine S.

Between 10 and 30% of depressed patients, mostly bipolar, develop a therapy-resistant illness. The known causes of such chronic evolutions are discussed: misdiagnosis (underlying schizophrenia, personality disorder or dementia), drug-induced depression (neuroleptics), systemic disease (hypothyroidism, multiple sclerosis, cardiovascular or neoplastic disease etc.), or lack of efficacy (drug compliance, insufficient dosage). Remedies are suggested: adequate dosage, drug combination (Newcastle cocktail. tricyclic antidepressant + MAOI, imipramine + T3), carbamazepine in lithium-resistant cases, alprazolam, reduction in vanadium intake, sleep deprivation, psychosurgery.

PMID: 3088916 [PubMed - indexed for MEDLINE]

SOURCE :

http://www.ncbi.nlm.nih.gov/entrez/query.f...8916&query_hl=4

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