Jump to content
Using an Ad Blocker? Consider adding HadIt.com as an exception. Hadit.com is funded through advertising, ad free memberships, contributions and out of pocket. ×

Can A Hormone Injection Reverse Ptsd? -- Va Starts Testing


This thread is over 365 days old and has been closed.

Please post your question as a New Topic by clicking this link and choosing which forum to post in.

For almost everything you are going to want to post in VA Claims Research.

If this is your first time posting. Take a moment and read our Guidelines. It will inform you of what is and isn't acceptable and tips on getting your questions answered. 

 

Remember, everyone who comes here is a volunteer. At one point, they went to the forums looking for information. They liked it here and decided to stay and help other veterans. They share their personal experience, providing links to the law and reference materials and support because working on your claim can be exhausting and beyond frustrating. 

 

This thread may still provide value to you and is worth at least skimming through the responses to see if any of them answer your question. Knowledge Is Power, and there is a lot of knowledge in older threads.

 

spacer.png

Recommended Posts

http://www.dallasnews.com/sharedcontent/dw...n1.3ec50b2.html

Injections might help treat post-traumatic stress disorder

After UT Southwestern study, Dallas VA testing hormone on veterans

05:41 AM CDT on Wednesday, September 13, 2006

By SUE GOETINCK AMBROSE / The Dallas Morning News

A simple injection can ease the anxiety that comes with reliving a traumatic memory, according to a new study on mice conducted by Dallas researchers. Scientists at the Dallas Veterans Affairs Medical Center are testing whether a similar medication can relieve post-traumatic stress disorder.

An estimated 5.2 million Americans suffer from the disorder. Combat, an assault or a natural disaster can trigger the condition, which can persist for months or years. Available treatments include psychotherapy and counseling, but no definitive medication exists.

In the new study, scientists at UT Southwestern Medical Center tried to simulate post-tramautic stress disorder in lab mice. The researchers placed mice in a box and gave them a mild but unpleasant electric shock to the feet. When the mice were placed in the box again – with no electric shock – they froze in fear. But when the mice were given an injection of a natural stress hormone, their fear decreased.

The researchers "have made an important discovery that might give us a new therapeutic approach to treating phobias and post-traumatic stress disorder," David Sweatt, a neuroscientist and memory researcher at the University of Alabama at Birmingham, wrote in an e-mail.

The research, appearing in today's issue of the Journal of Neuroscience, stemmed from previous studies showing that people with the disorder have lower-than-normal surges of a stress hormone, corticosterone. That suggested that the hormone – part of the body's biochemical arsenal for dealing with stressful situations – might normally help counteract the anxiety brought on by traumatic memories.

Based on the new mouse tests, that idea seems to be holding up, said Dr. Craig Powell, the UT Southwestern neuroscientist who led the study. The corticosterone injections, he said, seem to help the brain replace the old memory – that the box means an electric shock – with a new one that says the box is now safe.

"We're not erasing the memory, but we're saying, 'Hey, this isn't so bad,' " Dr. Powell said.

Dr. Powell and his colleagues found that the timing of the injection was key. The injection had to be given right after triggering the box-shock memory, he said. Giving the injection before putting the mouse in the box, or without putting the mouse in the box, had no effect.

Based on the mouse experiments, it may be that people prone to post-traumatic stress disorder don't, for whatever reason, extinguish the fear associated with their memories because they don't produce enough corticosterone, said Dr. Robert Greene, a UT Southwestern psychiatrist and neuroscientist who participated in the study. If that's the case, then giving stress hormone injections just after reliving a traumatic memory might help treat the disorder.

Dr. Greene said researchers hope to replace the "malfunction" in the brain.

"Under normal conditions, the hormone system enhances its own extinction of a fear memory," he said. "What's abnormal is when the extinction doesn't happen."

The Dallas VA Medical Center has enrolled about 20 veterans with combat-related post-traumatic stress disorder, giving some of them a stress hormone injection and the others a placebo after triggering traumatic memories. At this point, the researchers don't know which veterans are getting which injection. When the study is complete, the researchers will figure out who got the medication and see whether it was helpful in treating the disorder.

The other UT Southwestern researchers involved in the study were Wen-Hui Cai, Jacqueline Blundell and Jie Han. Dr. Cai and Dr. Greene are also on staff at the Dallas VA Medical Center.

Edited by jessejames
Link to comment
Share on other sites

  • Replies 0
  • Created
  • Last Reply

Top Posters In This Topic

Popular Days

Top Posters In This Topic

This thread is over 365 days old and has been closed.

Please post your question as a New Topic by clicking this link and choosing which forum to post in.

For almost everything you are going to want to post in VA Claims Research.

If this is your first time posting. Take a moment and read our Guidelines. It will inform you of what is and isn't acceptable and tips on getting your questions answered. 

 

Remember, everyone who comes here is a volunteer. At one point, they went to the forums looking for information. They liked it here and decided to stay and help other veterans. They share their personal experience, providing links to the law and reference materials and support because working on your claim can be exhausting and beyond frustrating. 

 

This thread may still provide value to you and is worth at least skimming through the responses to see if any of them answer your question. Knowledge Is Power, and there is a lot of knowledge in older threads.

 

spacer.png

Guest
This topic is now closed to further replies.


  • veterans-crisis-line.jpg
    The Veterans Crisis Line can help even if you’re not enrolled in VA benefits or health care.

    CHAT NOW

  • question-001.jpeg

    Have Questions? Get Answers.

    Tips on posting on the forums.

    1. Post a clear title like ‘Need help preparing PTSD claim’ or “VA med center won’t schedule my surgery instead of ‘I have a question.
       
    2. Knowledgeable people who don’t have time to read all posts may skip yours if your need isn’t clear in the title.
      I don’t read all posts every login and will gravitate towards those I have more info on.
       
    3. Use paragraphs instead of one massive, rambling introduction or story.
       
      Again – You want to make it easy for others to help. If your question is buried in a monster paragraph, there are fewer who will investigate to dig it out.
     
    Leading too:

    exclamation-point.pngPost straightforward questions and then post background information.
     
    Examples:
     
    • Question A. I was previously denied for apnea – Should I refile a claim?
      • Adding Background information in your post will help members understand what information you are looking for so they can assist you in finding it.
    Rephrase the question: I was diagnosed with apnea in service and received a CPAP machine, but the claim was denied in 2008. Should I refile?
     
    • Question B. I may have PTSD- how can I be sure?
      • See how the details below give us a better understanding of what you’re claiming.
    Rephrase the question: I was involved in a traumatic incident on base in 1974 and have had nightmares ever since, but I did not go to mental health while enlisted. How can I get help?
     
    This gives members a starting point to ask clarifying questions like “Can you post the Reasons for Denial of your claim?”
     
    Note:
     
    • Your first posts on the board may be delayed before they appear as they are reviewed. This process does not take long.
    • Your first posts on the board may be delayed before they appear as they are reviewed. The review requirement will usually be removed by the 6th post. However, we reserve the right to keep anyone on moderator preview.
    • This process allows us to remove spam and other junk posts before hitting the board. We want to keep the focus on VA Claims, and this helps us do that.
  • Most Common VA Disabilities Claimed for Compensation:   

    tinnitus-005.pngptsd-005.pnglumbosacral-005.pngscars-005.pnglimitation-flexion-knee-005.pngdiabetes-005.pnglimitation-motion-ankle-005.pngparalysis-005.pngdegenerative-arthitis-spine-005.pngtbi-traumatic-brain-injury-005.png

  • VA Watchdog

  • Can a 100 percent Disabled Veteran Work and Earn an Income?

    employment 2.jpeg

    You’ve just been rated 100% disabled by the Veterans Affairs. After the excitement of finally having the rating you deserve wears off, you start asking questions. One of the first questions that you might ask is this: It’s a legitimate question – rare is the Veteran that finds themselves sitting on the couch eating bon-bons … Continue reading

×
×
  • Create New...

Important Information

{terms] and Guidelines