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Cortical/subcortical Disease Burden And Cognitive Impairment In Patients With Multiple Sclerosis

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Cortical/Subcortical Disease Burden and Cognitive Impairment in Patients with Multiple Sclerosis

Conclusions:

Our study shows that the presence and extent of MS disease in the cortical and subcortical regions significantly influence the cognitive functions of these patients. MT imaging findings suggest that both the macro- and microscopic disease burden play an important role, and indicate that MTR histographic analysis might be useful for monitoring the evolution of cognitive impairment in MS.

http://www.ajnr.org/cgi/content/full/21/2/402

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